當前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標記一抗 > bs-7685R-PEPE標記的心臟特異性絲氨酸蛋白酶抗體
簡要描述:Corin was first described as a trypsin-like serine proteinase in the heart which processed pro-atrial natriuretic peptide into the active form ANP. Corin cleaves pro-ANP at Arg98/Ser-99, and blocking Corin message inhibits pro-ANP processing. Null mutant mice lacking Corin develop hypertension, and a series of missense mutations have been identified in humans with high blood pressure and hypertension. Corin is a member of the type-II transmembrane serine proteinases, such as Hepsin, Epitheli
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